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Genome Editing in Neurosciences

ISBN: 978-3-319-60192-2
Editorial: Springer Nature
Licencia: Creative Commons (by)
Autor(es): Jaenisch, Rudolf

One of the main challenges to understanding the onset and progression of human
disease is to develop effective model systems that combine known genetic elements
with disease-associated phenotypic readouts. The identification of genes linked to
familial forms of diseases such as cystic fibrosis, sickle cell anemia or monogenetic
forms of neurodegenerative disorders has fundamentally changed our understanding of many diseases and provided vital clues into the underlying pathogenesis.
[Cham: 2017]

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